Type 2 Research Grant
Prof Tony Futerman said; ‘There has been some dispute in the field about whether nerve cells are themselves affected in type 2 Gaucher, but we have provided data over the past few years showing defective calcium homeostasis in neurons from animal models of type 2 GD and also in human brain (obtained post-mortem). We are continuing to define the biochemical pathways that are affected as a result of these changes in calcium homeostasis, and this award will help us to pursue these studies, with a view to eventually identifying novel therapeutic approaches’.
Update - December 2008